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The SCALE trials showed liraglutide 3.0 mg producing approximately 8% body weight loss over 56 weeks, roughly half of what semaglutide achieves

Prioritize protein (0.7 to 1.0 grams per pound of target body weight), eat frequent small meals rather than large infrequent ones, limit high-fat foods during dose increases to reduce nausea, stay hydrated, and avoid alcohol (which worsens both GI side effects and calorie intake)

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Research in chronic venous leg ulcers (notoriously difficult to heal) demonstrated that GHK-Cu treatment could accelerate closure and improve healing outcomes in this challenging patient population